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张 维 芬

一、个人简介

张维芬，博士，二级教授，山东省智能材料与再生医学工程技术研究中心、药学实验教学中心主任，山东省黄大年式教师团队及校优秀研究生导师团队带头人。国务院特贴专家，山东省突贡专家、智库专家，获全国优秀教师、山东省优秀科技工作者荣誉称号。长期从事药物新剂型、新技术及智能生物材料开发应用研究。主持国家自然科学基金等科研项目16 项；获山东省科学技术进步二等奖等14项奖励；近5年发表SCI 论文50 余篇，获国家及美国、日本授权发明专利 27件。与诺一迈尔（山东）医学科技有限公司等7家企业合作。兼中国中医药信息学会临床分会常务理事等社会兼职。目前带教在读研究生7人。邮箱：zwf2024@126.com。

二、研究方向

, , , , , , , , . Bletilla striata polysaccharide-based dissolving microneedle patch integrated with nanoparticles for promoting hair regrowth, Int J Biol Macromol, 2025, PMID:39892550, doi: 10.1016/j.ijbiomac.2025.140336.

2、Zhengchao Yuan, Siyuan Wu, Liwen Fu, Muhammad Shafiq, Yuqing Lian, Peng Li, Xinyi Wang, Hao Feng, Shuqi Lou, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Weifen Zhang, Xiumei Mo, Shichao Jiang. Eggshell membrane loaded with inorganic particles from egg shell for soft and hard tissue regeneration, Composites Part B, 2025,292,112071.  

3、Shengxiu Wen, Hanqiang Zhao, Ying Zhang, Dadong Cao,MeijunLiu, HongmingYang, Weifen Zhang.Multifunctional nanofiber membranes constructed by microfluidic blow-spinning to inhibit scar formation at early intervention stage, ACS Appl Mater Interfaces, 2024,  16(39):53042-53059.

4、Yunfei Han, Mingxia Jiang, Yanju Sun, Wenqiang Chen, Yanli Zhao, Xiuwen Guan, Weifen Zhang. Efficient chemo-immunotherapy leveraging minimalist electrostatic complex nanoparticle as “in situ” vaccine integrated tumor ICD and immunoagonist, J Adv Res, 2024, 16:S2090-1232(24)00108-5.0

5、Mingxia Jiang, Wenqiang Chen, Yanju Sun, Jun Zeng, Lina Ma, Jianping Gong, Xiuwen Guan, Keliang Lu, Weifen Zhang. Synergistically enhanced cancer immunotherapy by combining protamine-based nanovaccine with PD-L1 gene silence nanoparticle, Int J Biol Macromol, 2023, 242:125223.

6、Liping Zhao, Mingxia Jiang, Zhilu Xu, Fengshuo Sun, Xinghan Wu, Mogen Zhang, Xiuwen Guan, Jinlong Ma, Weifen Zhang. Selective thermotherapy of tumor by self-regulating photothermal conversion system, J Colloid Interf Sci, 2022, 605:752-765.

7、Mingxia Jiang, Wenqiang Chen, Wenjing Yu, Zhiwei Xu, Xinyue Liu, Qingmiao Jia, Xiuwen Guan, Weifen Zhang. Sequentially pH-responsive drug delivery nanosystem for tumor immunogenic cell death and cooperating with immune checkpoint blockade for efficient cancer chemoimmunotherapy, ACS AMI, 2021,13, 37, 43963-43974.

8、Yonghong Wang, Hongli Yu, Saisai Wang, Chengcheng Gai, Xiaoming Cui, Zhilu Xu, Wentong Li, Weifen Zhang. Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel, Mat Sci Eng C-mater, 2021, 119: 111442.

9、Jun Zeng, Yanju Sun, Shuo Sun, Mingxia Jiang, Daijuan Zhang, Wentong Li, Zhijun Liu, Hongcai Shang, Xiuwen Guan, Weifen Zhang. Leveraging nanodrug delivery system for simultaneously targeting tumor cells and M2 tumor-associated macrophages for efficient colon cancer therapy. ACS AMI, 2022, 14, 50475-50484.

10、Xiaoming Cui, Fang Zhang, Yanyan Zhao, Pan Li, Ting Wang, Zhilu Xu, Jingjing Zhang, Weifen Zhang. A novel ligand-modified nanocomposite microparticles improved efficiency of quercetin and paclitaxel delivery in the non-small cell lung cancer, Drug Deliv, 2022.12, 29(1):3123-3133.